The recipe to make a habitable planet like our own Earth requires a relatively small rocky planet, at the right distance from the host star, with a not too thick atmosphere rich in volatiles and capable of developing complex organic chemistry. The GENESIS-SKA project, supported as PRIN-INAF, is carrying on studies of planet formation, and pre-biotic chemical complexity, in the context of preparation of SKA Key Programmes. More specifically, we are featuring synergies between astronomical observational and modeling efforts, laboratory experiments, and quantum-chemical computations.